John Gurdon

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John Gurdon

significant hurdles that are only just beginning to be overcome. Complex cell behaviors, such as migration, result from coordinated activity of several individual component processes. While considerable progress has been made in identifying molecules related to migration and elucidating the mechanisms by which they function in a component process, understanding the integration of these various ...

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An interview with John Gurdon.

John Gurdon is a Distinguished Group Leader in the Wellcome Trust/Cancer Research UK Gurdon Institute and Professor Emeritus in the Department of Zoology at the University of Cambridge. In 2012, he was awarded the Nobel Prize in Physiology or Medicine jointly with Shinya Yamanaka for work on the reprogramming of mature cells to pluripotency, and his lab continues to investigate the molecular me...

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Sir John Gurdon: father of nuclear reprogramming.

Sir John Gurdon founded the field of nuclear reprogramming. His work set the stage for the ever burgeoning area of stem cell biology and regenerative medicine. Here I provide personal reflections on times I shared with John Gurdon and professional reflections of the impact of his ground-breaking research on my own development as a scientist and on the field in general. His paradigm-shifting exp...

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Sir John Gurdon: Godfather of cloning

S ir John Gurdon's famous frog cloning experiments of the 1960s and '70s answered a question that had been hanging over cell biologists since before the turn of the century: are the cells of an adult organism genetically identical to the fertilized egg from which they are derived? Briggs and King in the early '50s suggested that cells' genetic material is irreversibly altered as they begin to d...

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"The Developmental Capacity of Nuclei Taken from Intestinal Epithelium Cells of Feeding Tadpoles" (1962), by John B. Gurdon

In 1962 researcher John Bertrand Gurdon at the University of Oxford [3] in Oxford, England conducted a series of experiments on the developmental capacity of nuclei taken from intestinal epithelium [4] cells of feeding tadpoles. In the experiments, Gurdon conducted nuclear transplantation, or cloning [5], of differentiated cells, or cells that have already specialized to become one cell type or...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2003

ISSN: 0960-9822

DOI: 10.1016/j.cub.2003.09.015